Primary Immunodeficiency
Learn the warning signs of children with immune system problems or primay immunodeficiency, including severe, frequent infections that require intravenous antibiotics and hospitalization.
Daycare Syndrome And Frequent Infections
Learn about frequent infections in children that attend daycare and what the signs of a primary immunodeficiency or immune system problem might be.
Learn about frequent infections in children that attend daycare and what the signs of a primary immunodeficiency or immune system problem might be.
Primary Immunodeficiency Glossary
A glossary of terms used to describe primary immunodeficiency disorders.
A glossary of terms used to describe primary immunodeficiency disorders.
What Is Primary Immune Deficiency?
Review what a primary immune deficiency is and what type of doctors can test for it.
Review what a primary immune deficiency is and what type of doctors can test for it.
Chronic Granulomatous Disease
Children with CGD develop recurrent skin infections, abscess, and boils.
Children with CGD develop recurrent skin infections, abscess, and boils.
X-Linked Agammaglobulinemia
Infants with XLA develop frequent pus-producing infections of the inner ear, lungs, and sinuses. Serious infections can develop in the bloodstream and internal organs. They tend to cope well with most short-term viral infections, but are very susceptible to chronic viral infections such as hepatitis, polio, and ECHO viruses.
Infants with XLA develop frequent pus-producing infections of the inner ear, lungs, and sinuses. Serious infections can develop in the bloodstream and internal organs. They tend to cope well with most short-term viral infections, but are very susceptible to chronic viral infections such as hepatitis, polio, and ECHO viruses.
Severe Combined Immunodeficiency
Children with SCID get many serious or life-threatening infections, especially pneumonia, meningitis, and sepsis (blood infection).
Children with SCID get many serious or life-threatening infections, especially pneumonia, meningitis, and sepsis (blood infection).
Hyper-IgE (HIE) Syndrome
This rare condition is also called Job syndrome. Health care experts have reported only 200 cases of HIE. People with HIE have very high levels of the IgE antibody. HIE causes recurring bacterial infections and other complications.
This rare condition is also called Job syndrome. Health care experts have reported only 200 cases of HIE. People with HIE have very high levels of the IgE antibody. HIE causes recurring bacterial infections and other complications.
Hyper-IgM Syndrome
Hyper-IgM is a rare immunodeficiency disease in which the immune system fails to produce IgA and IgG antibodies.
Hyper-IgM is a rare immunodeficiency disease in which the immune system fails to produce IgA and IgG antibodies.
Common Variable Immunodeficiency
Children with CVI have frequent bacterial infections, painful swollen joints, digestive tract problems, and an enlarged spleen and swollen glands.
Children with CVI have frequent bacterial infections, painful swollen joints, digestive tract problems, and an enlarged spleen and swollen glands.
Interferon-Gamma Receptor (IFNGR) Deficiency
This very rare inherited disorder causes individuals to be more susceptible to mycobacteria that cause tuberculosis, as well as other types of mycobacteria, and infections caused by salmonella bacteria.
This very rare inherited disorder causes individuals to be more susceptible to mycobacteria that cause tuberculosis, as well as other types of mycobacteria, and infections caused by salmonella bacteria.
Selective IgA Deficiency
People with this deficiency lack immunoglobulin A (IgA), a type of antibody that protects against infections of the mucous membranes lining the mouth, airways, and digestive tract.
People with this deficiency lack immunoglobulin A (IgA), a type of antibody that protects against infections of the mucous membranes lining the mouth, airways, and digestive tract.
Leukocyte Adhesion Deficiency
LAD is a rare PI disease, found in one out of every million people. This disease causes recurrent, life-threatening infections. Phagocytes cannot find their way to the site of infection to fight off invading germs.
LAD is a rare PI disease, found in one out of every million people. This disease causes recurrent, life-threatening infections. Phagocytes cannot find their way to the site of infection to fight off invading germs.
Warning Signs of Primary Immunodeficiency
Review the 10 warning signs that might indicate that your child has a primary immunodeficiency or problem with their immune system causing frequent infections.
Review the 10 warning signs that might indicate that your child has a primary immunodeficiency or problem with their immune system causing frequent infections.
Jeffrey Modell Foundation
The Jeffrey Modell Foundation was established by Vicki and Fred Modell in memory of their son Jeffrey, who died at the age of 15 of a Primary Immunodeficiency. The Foundation is dedicated to early and precise diagnosis, meaningful treatments, and ultimately cures of Primary Immunodeficiencies.
The Jeffrey Modell Foundation was established by Vicki and Fred Modell in memory of their son Jeffrey, who died at the age of 15 of a Primary Immunodeficiency. The Foundation is dedicated to early and precise diagnosis, meaningful treatments, and ultimately cures of Primary Immunodeficiencies.
Primary Immune Deficiency
Learn about the different types of primary immune deficiencies or immune system problems that cause frequent infections, including Selective IgA Deficiency, Common Variable Immunodeficiency (CVI), X-Linked Agammaglobulinemia (XLA), Severe Combined Immunodeficiency (SCID), Chronic Granulomatous Disease (CGD), and more in this Patient and Family Handbook from the Immune Deficiency Foundation.
Learn about the different types of primary immune deficiencies or immune system problems that cause frequent infections, including Selective IgA Deficiency, Common Variable Immunodeficiency (CVI), X-Linked Agammaglobulinemia (XLA), Severe Combined Immunodeficiency (SCID), Chronic Granulomatous Disease (CGD), and more in this Patient and Family Handbook from the Immune Deficiency Foundation.