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Clinical Trials for Children and Teens

Clinical trials are medical research studies that evaluate new drugs and other treatments and new uses for established treatments to determine if they are safe and effective.

Understanding Clinical Trials
An introduction to clinical trials, include what a clinical trial is, different types and phases of clinical trials, informed consent, how to decide whether to participate in a clinical trial, including potential benefits and risks, and how to find out if you are eligible.

Clinical Trials for Children
All clinical trials for children from birth to age seventeen years at clinicaltrials.gov.

Clinical Trials
Learn about clinical research studies for both federally and privately funded trials "of experimental treatments for serious or life-threatening diseases or conditions."  Search by entering a keyword, do a 'Focused Search' or 'Browse by Condition' to find an appropriate clinical trial for your child.

Pediatric Clinical Trials
Clinical Trials in Pediatrics/Neonatology from Centerwatch, including treatment of allergies, anorexia, anxiety disorders, asthma, cerebral palsy, common cold, ear infections, eczema, growth hormone deficiences, hypertension, influenza, irritable bowel syndrome, migraine, severe short stature, strep throat and wilm's tumor.

Growth Hormone Trials
Clinical Trials for children who may benefit from the use of growth hormone, including children with cystic fibrosis; renal osteodystrophy and end stage renal disease requiring dialysis; Turner's Syndrome; Dwarfism; Osteogenesis Imperfecta; and short stature.

Children’s Oncology Group
The Children's Oncology Group has a mission to "cure and prevent childhood and adolescent cancer through scientific discovery and compassionate care." Locate a treatment center in your area.

Children with Arthritis
Clinical Trials for children with arthritis, including Juvenile Rheumatoid Arthritis (JRA), systemic sclerosis, systemic lupus erythematosus (SLE), Psoriatic Arthritis, Sjogren's Syndrome, Rheumatic Fever and Dermatomyositis. Current trials may include the use of cyclophosphamide, enbrel, total body irratdiation, and bone marrow transplantation.

Children with Asthma
Clinical trials for treating children with asthma. Current clinical trials may include the effects of reducing indoor allergen exposures, response to allergy shots, use of Enbrel in the treatment of asthma, and the effects of reducing enviornmental tobacco smoke.

Children with ADHD
Clinical Trials for children with attention deficit disorder. Current trials may include the treatment of Attention Deficit Hyperactivity Disorder in preschool and school-age children, nutrient intake, MRI brain imaging, stimulant drug treatment, biological markers, genetic aspects of ADD, lead exposure and treatment of youth with ADHD and anxiety.

Children with Austism
Clinical Trials for children with autism. Current trials may include the use of fluoxetine (Prozac), and brain imaging.

Children with Bipolar Disorder
Clinical Trials for children with bipolar disorder. Current trials may include a bipolar treatment study, symptoms and causes of bipolar disease in children and adolescents, MRI brain imaging, and genetics.

Children with Cancer
Clinical Trials for children with cancer, including childhood soft tissue sarcoma; childhood liver cancer; bone cancer; brain tumors; kidney tumors; leukemia (ALL and AML); lymphoma; eye cancer; rhabdomyosarcoma; neuroblastoma; and Hodgkin's disease. Current trials may include chemotherapy, bone marrow transplantation, and stem cell transplantation.

Children with Cystic Fibrosis
Clinical trials to find new treatments for children with cystic fibrosis. Current trials may include use of tobramycin, growth hormone, pressure support ventilation, and gene transfer therapy.

Children with Depression
Clinical Trials for children with depression. Current trials may include depression in juvenile diabetics, effects of Fluoxetine (Prozac), and treatments for bipolar disorder and postpartum depression.

Children with Diabetes Mellitus
Clinical trials to find new treatments for children with diabetes mellitus. Current trials may include the diabetes prevention study, islet transplantation, use of xenical in children and adolescents, and preventing complications of diabetes.

Children with Epilepsy
Clinical trials to find new treatments for children with seizures and epilepsy. Current trials may include info on ketogenic diets, taking antiepileptic drugs during pregnancy, and managing children with difficult to control epilepsy.

Children with Hepatitis
Clinical Trials for children with hepatitis, including hepatitis C, chronic hepatitis B, biliary liver cirrhosis, hemochromatosis, and HIV infections. Current trials may include comparing single photon emission computed tomography (spect) and liver biopsy, long-term interferon treatment, use of ribavirin, lamivudine, and combination drug therapy.

Children with Herpes
Clinical Trials for children with herpes, including herpes simplex encephalitis, . Current trials may include the use of Valacyclovir (Valtrex), and suppressive therapy with oral acyclovir suspension following neonatal herpes simplex virus (hsv).

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