1. Home
  2. Health
  3. Pediatrics
Vincent Iannelli, M.D.
Pediatrics Blog

By Vincent Iannelli, M.D., About.com Guide to Pediatrics

Kids and Antidepressants

Thursday August 28, 2003
Depression is a serious pediatric problem, with experts estimating that 3% of children and 8% of teens have depression.

Barriers to these kids getting help often includes that many pediatricians don't have experience diagnosing or treating depression and few medicines are approved for use in children.

Fortunately, new studies in the Journal of the American Medical Association has shown that 'sertraline {Zoloft} is an effective and well-tolerated short-term treatment for children and adolescents with MDD.'

In the studies that the article describes, 376 children and adolescents aged 6 to 17 years with depression were either given Zoloft or a placebo. After 10 weeks, the studies showed that Zoloft 'was found to be more effective than placebo for treatment of pediatric MDD' (major depression disorder). In addition, the risk of suicide was no greater in the kids who took Zoloft, which is good news because some other studies have raised concern about an increased risk of suicide in children that took other SSRI antidepressants, like Paxil.

Although not formally approved by the FDA for children with depression, this article concludes that Zoloft is 'an effective, safe, and well-tolerated short-term treatment for children and adolescents with MDD.' Zoloft is approved for kids over age 6 with Obsessive-Compulsive Disorder and is available as an oral concentrated syrup for kids who can't swallow pills.

For more information:

Comments

No comments yet. Leave a Comment

Leave a Comment

Line and paragraph breaks are automatic. Some HTML allowed: <a href="" title="">, <b>, <i>, <strike>

Explore Pediatrics
About.com Special Features

Learn how you can reduce your your numbers with these nutrition and exercise tips. More >

Keep yourself, and your family, happy and healthy this fall with these tips. More >

  1. Home
  2. Health
  3. Pediatrics

©2009 About.com, a part of The New York Times Company.

All rights reserved.